Never in the history of civilization have there been so many ways to manipulate sound. Purists tend to dismiss music made with the numerous contemporary mediums, but I doubt 20th-century experimentalists John Cage, Harry Partch, Raymond Scott or Sun Ra would have felt that way. I’m confident that they would have embraced and thrilled with a world of ever-increasing creative possibilities. A wide range of 21st-century audio adventurers will take the stage at the 25 Watt for the International Noise Conference on Wednesday, July 6. Presented by Rat Bastard and the Laundryroom Squelcher, the night of combative cacophonies features 15-minute performances by analog and digital provocateurs Stabbed in the Face, Crack Bytch, Yoga Demon, Flesh Control and many others. Definitely not for the faint of heart, doors open for the system of assaults at 7 p.m. Admission is $5. 25wattrva.com.